60例临床手术犬舒眠宁静脉麻醉效果的评价及其对肝、肾功能的影响

doi:10.11843/j.issn.0366-6964.2013.12.022

畜牧兽医学报 ›› 2013, Vol. 44 ›› Issue (12): 2007-2015.doi: 10.11843/j.issn.0366-6964.2013.12.022

60例临床手术犬舒眠宁静脉麻醉效果的评价及其对肝、肾功能的影响

刘澜¹，李培德²，侯加法^1*

（1. 南京农业大学动物医学院，南京 210095； 2. 温州科技职业学院动物科学系，温州 325006）

收稿日期:2013-06-26 出版日期:2013-12-23 发布日期:2013-12-23
通讯作者: 侯加法，教授，博士生导师，主要从事小动物麻醉与临床应用研究，E-mail: jfhou@njau.edu.cn
作者简介:刘澜（1987-），女，河南新乡人，硕士，主要从事小动物麻醉与临床应用研究，E-mail：akeliusi2007@126.com；李培德（1982-），男，山东诸城人，讲师，博士，E-mail：su-2737@163.com。二人为共同第一作者
基金资助:
国家自然科学基金（31272618；30972234）

Anesthetic Evaluation of Shumianning Injected Intravenously in 60 Clinical Surgical Dogs and Its Effect on the Hepatic and Renal Function

LIU Lan¹,LI Pei-de²,HOU Jia-fa^1*

(1.College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China;2.Department of Animal Science, Wenzhou Vocational College of Science & Technology, Wenzhou 325006, China)

Received:2013-06-26 Online:2013-12-23 Published:2013-12-23

摘要/Abstract

摘要：

拟在临床手术病犬静脉舒眠宁麻醉后评价其麻醉效果及其对犬肝、肾功能的影响。以舒眠宁注射液用于门诊手术病犬60例，记录麻醉起效时间(T1)、单次注射麻醉维持时间(T2)、手术时间(T3)、苏醒时间(T4)、追加麻醉次数(N)及总用药量(SUM)。手术过程中评估犬各项生理参数，手术麻醉效果及苏醒质量，分别于麻醉前和苏醒时测定其血液生化和血常规参数。结果表明，犬舒眠宁麻醉后，其手术时间、苏醒时间、追加麻醉次数及总用药量依手术类型及动物体型而定。麻醉起效时间为（32.2±1.4）s；单次注射舒眠宁麻醉维持时间为（25.7±1.6）min，苏醒时间为（32.6±2.6）min。手术麻醉效果为优级85.0% (51/60)，良级11.7% (7/60)，可级3.3% (2/60)。苏醒质量评分为3.8±0.1，苏醒期平稳，术后恢复良好。麻醉后血常规、总蛋白、白蛋白和球蛋白水平有所下降，但均在正常生理范围内；肝、肾功能正常。手术麻醉效果显示，舒眠宁注射液适用于犬的临床麻醉，麻醉效果确实，苏醒过程平稳，对肝、肾功能无明显影响。

Abstract:

The purpose of this study was to evaluate the anesthetic quality of Shumianning which was injected intravenously and the effect on the hepatic and renal function in clinical surgical Dogs. Shumianning injection was administered intravenously in sixty dogs which were operative in the clinic. The anesthetic onset time (T1), the anesthesia duration of single injection of Shumianning (T2), the time of operation (T3) and awaking(T4) as well as the adding times(N) of Shumianning and the consumption of Shumianning (SUM) were recorded. Physiological parameters, anesthetic and recovery quality were assessed in the period of operation. Blood routine test and biochemical parameters were measured before and after anesthesia. The results showed that T3, T4, N and SUM were dependent on the operation type and the body size. T1 was （32.2±1.4）s, T2 was （25.7±1.6）min, T4 was （32.6±2.6）min, the recovery quality score was 3.8±0.1. Anesthetic quality was classed as excellent (51/60, 85.0%), good (7/60, 11.7%) and fair (2/60, 3.3%). Biochemical parameters of TP, ALB, GLB, WBC, RBC, HGB and HCT were in the normal range, although there were a slight declined (P＜0.05). The clinical anesthesia status of Shumianning administered intravenously in dogs for surgical treatment was satisfying. The duration of anesthesia and recovery was smooth. Shumianning had no significant effect on hepatic and renal function.

中图分类号:

刘澜，李培德，侯加法. 60例临床手术犬舒眠宁静脉麻醉效果的评价及其对肝、肾功能的影响[J]. 畜牧兽医学报, 2013, 44(12): 2007-2015.

LIU Lan,LI Pei-de,HOU Jia-fa. Anesthetic Evaluation of Shumianning Injected Intravenously in 60 Clinical Surgical Dogs and Its Effect on the Hepatic and Renal Function[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2013, 44(12): 2007-2015.

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60例临床手术犬舒眠宁静脉麻醉效果的评价及其对肝、肾功能的影响

Anesthetic Evaluation of Shumianning Injected Intravenously in 60 Clinical Surgical Dogs and Its Effect on the Hepatic and Renal Function

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